Who Can Participate?
Males or females, ≥ 18 years of age with chronic spontaneous urticaria (CSU) may be eligible to participate.
Inclusion Criteria:
– Recurrent pruritic wheals (itchy bumps) with or without angioedema (swelling in deeper layers of skin) for ≥ 6 weeks at any time prior to screening despite treatment with a H1AH
– Must have been on a stable dose and regimen containing a second-generation H1AH at approved or increased dose as background therapy for the treatment of CSU for ≥ 4 weeks prior to randomization
Participant Info:
How Long Will The Study Last?
No Doctors Found
Similar Trials
No Similar Trials FoundThe following information is from ClinicalTrials.gov
Last Update Posted: February 11, 2025
NCT06455202
Celldex Therapeutics
Brief Summary:
The purpose of this study is to establish the efficacy, safety and tolerability of barzolvolimab in adult participants with Chronic Spontaneous Urticaria (CSU) inadequately controlled by non-sedating second generation H1-antihistamines in comparison to placebo.
Condition or Disease:
Chronic Spontaneous Urticaria
Intervention/Treatment:
Biological: barzolvolimab Biological: barzolvolimab Biological: barzolvolimab,Biological: Matching placebo Biological: barzolvolimab,Biological: Matching placeboPhase:
PHASE 3
Ages Eligible for Study:
18 Years and older (ADULT,OLDER_ADULT)
Sexes Eligible for Study:
ALL
Terms and Conditions – ClinicalTrials.gov
Purpose of ClinicalTrials.gov Database. The U.S. National Institutes of Health, Department of Health and Human Services, through its National Library of Medicine, has developed ClinicalTrials.gov to provide patients, family members, and members of the public current information about clinical research studies.
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Last Revised July 2024
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