Who Can Participate?
Adults (≥ 18 years of age) who have plaque psoriasis, may be eligible to participate.
Inclusion Criteria:
Participant Info:
How Long Will The Study Last?
Participation will last about 106 weeks and involve about 14 visits to the study research site (plus 2 phone visits).
After you have completed the study, you may have the opportunity to continue receiving ORKA-001 through another study. The study team will discuss this with you in further detail.
Waterloo - Alliance Clinical Trials
Toronto - Research Toronto
Peterborough - SKiN Centre for Dermatology
Markham - Lynderm Research Inc.
London - DermEffects
Surrey - Dr. Chih-ho Hong Medical Inc.
No Doctors Found
Similar Trials
No Similar Trials FoundThe following information is from ClinicalTrials.gov
Last Update Posted: August 18, 2025
NCT07090330
Oruka Therapeutics, Inc.
Brief Summary:
This is a multicenter, randomized, double-blinded, placebo-controlled, proof-of-concept study to evaluate the efficacy, safety, tolerability, and pharmacokinetics of ORKA-001 in adult participants with moderate-to-severe plaque psoriasis.
Condition or Disease:
Plaque Psoriasis
Intervention/Treatment:
Drug: ORKA-001 Induction Dose Other: Placebo Drug: ORKA-001 Maintenance Dose Drug: ORKA-001 Maintenance Dose Other: PlaceboPhase:
PHASE 2
Ages Eligible for Study:
18 Years and older (ADULT,OLDER_ADULT)
Sexes Eligible for Study:
ALL
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Last Revised July 2024
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