EVO756-CSU001 Enrolling

Chronic Spontaneous Urticaria Study (12 Weeks)


Treatment: Oral Age: 18+ Years


Who Can Participate?

Adults aged 18 and above with moderate to severe CSU may participate.

Inclusion Criteria

  • have a confirmed CSU diagnosis for ≥ 3 months with an inadequate response to H1 antihistamines
  • not have a history of diseases with urticaria or angioedema symptoms, other than CSU and symptomatic dermographism

Participant Information 

  • Participate and receive study treatment at no cost
  • Regular visits with study doctors who specialise in treating chronic spontaneous urticaria (7 visits)
  • Will receive an investigative oral treatment (study drug) or a placebo
  • Reimbursement for study-related expenses may be provided

How Long Will The Study Last?

  • 12 weeks

Participating Locations

COUNTRY
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United States
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Canada

Participating Experts

No Doctors Found

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The following information is from ClinicalTrials.gov

Last Update Posted: May 13, 2025

Official Title

A Randomized, Double-Blind, Placebo Controlled, Dose-Ranging Study Evaluating the Efficacy and Safety of EVO756 in Adults With Moderate to Severe Chronic Spontaneous Urticaria

ClinicalTrials.gov ID

NCT06873516

Sponsor

Evommune, Inc.

Study Description

  • Brief Summary:

    This study will evaluate the efficacy and safety of different doses of EVO756 in adults with moderate to severe chronic spontaneous urticaria (CSU).

  • Condition or Disease:

    Chronic Spontaneous Urticaria

  • Intervention/Treatment:

    Drug: EVO756 Drug: EVO756 Drug: EVO756 Drug: Placebo control
  • Phase:

    PHASE 2

  • Ages Eligible for Study:

    18 Years and older (ADULT,OLDER_ADULT)

  • Sexes Eligible for Study:

    ALL

Inclusion Criteria

  • have a confirmed CSU diagnosis for ≥ 3 months with an inadequate response to H1 antihistamines
  • not have a history of diseases with urticaria or angioedema symptoms, other than CSU and symptomatic dermographism

Terms and Conditions – ClinicalTrials.gov
Purpose of ClinicalTrials.gov Database. The U.S. National Institutes of Health, Department of Health and Human Services, through its National Library of Medicine, has developed ClinicalTrials.gov to provide patients, family members, and members of the public current information about clinical research studies.



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