Who Can Participate?
Male or female aged 18 or above with hidradenitis suppurativa (HS) may participate.
Inclusion Criteria
• Diagnosis of moderate to severe HS for at least 6 months
• Must have HS lesions present in at least 2 distinct anatomic areas
Participant Information
• Participate and receive study treatment at no cost
• Regular visits with study doctors who specialise in treating hidradenitis suppurativa (28 visits)
• Will receive either an investigative subcutaneous (SC) injection treatment (study drug) or a placebo
• Reimbursement for study-related expenses may be provided
How Long Will The Study Last?
• 60 weeks
Kelowna - Interior Dermatology Centre
Hamilton - LEADER Research
No Doctors Found
Similar Trials
No Similar Trials FoundThe following information is from ClinicalTrials.gov
Last Update Posted: November 17, 2025
NCT07170917
Sanofi
Brief Summary:
This is a Phase 2b, global, multicenter, sequential, randomized, double-blind, placebo-controlled, parallel group, dose-ranging study in participants with moderate to severe hidradenitis suppurativa. The purpose of this study is to assess the efficacy and safety of brivekimig in a dose-ranging study of participants with moderate to severe HS. Study details include: The study duration (per participant) will be up to approximately 60 weeks for participants not transitioning into the long-term extension (LTE) study and will be up to approximately 52 weeks for participants transitioning into the LTE study. The randomized treatment duration will be up to approximately 48 weeks.
Condition or Disease:
Hidradenitis Suppurativa
Intervention/Treatment:
Drug: Brivekimig Drug: Brivekimig Drug: Brivekimig Drug: PlaceboPhase:
PHASE2
Ages Eligible for Study:
18 Years and older (ADULT,OLDER_ADULT)
Sexes Eligible for Study:
ALL
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